منابع مشابه
Advances in corneal cell therapy.
Corneal integrity is essential for visual function. Transplantation remains the most common treatment option for advanced corneal diseases. A global donor material shortage requires a search for alternative treatments. Different stem cell populations have been induced to express corneal cell characteristics in vitro and in animal models. Yet before their application to humans, scientific and et...
متن کاملCell Therapy of Congenital Corneal Diseases with Umbilical Mesenchymal Stem Cells: Lumican Null Mice
BACKGROUND Keratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries. Our study aims to develop alternative treatment regimens for congenital corneal diseases of genetic mutation. METHODOLOGY/PRINCIPAL FINDINGS ...
متن کاملClinical Applicability of Stem Cell Therapy in Dental Diseases: A Systematic Review of Available Clinical Trials
Background: Developing cell-based therapeutic methods for the differentiation of various stem cells to the dental tissues could be a revolutionary step towards the use of cell therapy for dental disease. In the present study, we aimed to systematically review the literature to establish the efficiency of stem cells in treatment of various dental diseases. Methods: A literature search was perfo...
متن کاملRegenerative Cell Therapy for Corneal Endothelium.
Endothelial cell dysfunction as in Fuchs dystrophy or pseudophakic bullous keratopathy, and the limited regenerative capacity of human corneal endothelial cells (HCECs), drive the need for corneal transplant. In response to limited donor corneal availability, significant effort has been directed towards cell therapy as an alternative to surgery. Stimulation of endogenous progenitors, or transpl...
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ژورنال
عنوان ژورنال: Cornea
سال: 2016
ISSN: 0277-3740
DOI: 10.1097/ico.0000000000001010